Over 30 million men in the US, and 150 more globally suffer from Erectile Dysfunction (ED). Sildenafil (Viagra) has been proven to help men with ED recover their sexual performance, and improve their sex lives tremendously.
The nitric oxide-cyclic guanosine monophosphate pathway (NO-cGMP) that is involved in erection of the male sex organ (penis) has been suspected to also be involved in playing some part in sexual stimulation amongst women. The condition, known as Female Sexual Arousal Disorder (FSAD), is believed to impact almost 26% of American women. Tests were conducted to evaluate the safety and effectiveness of Sildenafil in the treatment of FSAD.
While the male and female sexual organs are totally different in their construction, the underlying source for driving them is muscle use. And at the heart of healthy muscle, whether it is uterine muscle, vaginal muscle or penile muscle, is the regular and unrestricted flow of blood to the region. Sildenafil has proven extremely effective in dealing with this problem.
Scientists involved in studies of the female gentile behaviour using Sildenafil, showed improved relaxation of the clitoral tissue. They also confirmed that phosphodiesterase type-5 (PDE5), which primarily causes ED amongst men, was also present in women’s Vagina, Clitoris and Labia muscles. PDE5 is therefore believed to also contribute to FSAD, and Sildenafil holds some promise for treating it. Women treated using Sildenafil reported slight improvement in libido and sexual arousal.
While these studies are not overly conclusive, other studies indicate that Sildenafil citrate could prove effective when treating women suffering from FSAD not as a primary cause, but secondary to other conditions such as MS, Diabetes or the use of antidepressants or were on Selective Serotonin Uptake Inhibitors (SSRIs).
In still other studies, it is believed that Sildenafil may yet prove beneficial for women undergoing In-vitro fertilization (IVF) treatments. The problem is that women need IVF due to weakness in the tissue lining in the uterus. Te study indicated that 70% of women who took Sildenafil experienced appreciable thickening of the uterine tissue lining, giving hope that the drug is effective.
Regardless of how the study’s results might be interpreted, there is clearly sufficient evidence to merit further investigations on whether Sildenafil can be an effective treatment for women’s health conditions. While women do seem to benefit from drugs like Sildenafil, because of the sensitivity involved, especially if women are pregnant or nursing, extreme care must be taken before using it for FSAD or any other ailment.